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Symbol Name ID |
Idua
iduronidase, alpha-L MGI:96418 |
| Darker colors indicate more annotations |
| Human Phenotypes | Endocardial fibroelastosis |
Abnormal heart valve morphology |
Cardiomyopathy |
Aortic regurgitation |
Aortic valve stenosis |
Mitral regurgitation |
Mitral stenosis |
Hypertension |
Pulmonary arterial hypertension |
Angina pectoris |
Splenomegaly |
Hepatosplenomegaly |
Abnormality of the tonsils |
Enlarged tonsils |
| Disease(s) Associated with IDUA | ||||||||||||||
| mucopolysaccharidosis Ih | ||||||||||||||
| mucopolysaccharidosis Ih/s | ||||||||||||||
| Scheie syndrome |
| Mouse Phenotypes | abnormal aorta elastic fiber morphology |
abnormal aorta smooth muscle morphology |
abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
abnormal mitral valve morphology |
enlarged mitral valve |
abnormal tricuspid valve morphology |
enlarged tricuspid valve |
abnormal endocardium morphology |
thick interventricular septum |
increased heart left ventricle septal wall thickness |
increased heart weight |
enlarged heart |
abnormal aortic valve morphology |
thick aortic valve cusps |
enlarged aortic valve |
abnormal heart ventricle morphology |
abnormal heart left ventricle outflow tract morphology |
increased heart left ventricle wall thickness |
increased heart left ventricle posterior wall thickness |
decreased cardiac output |
decreased ventricle muscle contractility |
abnormal cardiac muscle relaxation |
mitral valve regurgitation |
aortic valve regurgitation |
abnormal circadian regulation of heart rate |
decreased heart rate variability |
abnormal heart electrocardiography waveform feature |
prolonged P wave |
abnormal QRS complex |
prolonged QRS complex duration |
increased systemic arterial systolic blood pressure |
congestive heart failure |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||
| Iduatm1Clk/Iduatm1Clk | ||||||||||||||||||||||||||||||||||
| Iduatm1Efn/Iduatm1Efn | ||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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